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Nanotherapeutics lab

Publications

2025

Liu X, Abmanhal-Masarweh H, Iwanowytsch O, Okwelogu E, Arashvand K, Karabatsou K, D'Urso PI, Roncaroli F, Kostarelos K, Kisby T*, Hadjidemetriou M*.

Plasma-to-tumour tissue integrated proteomics using nano-omics for biomarker discovery in glioblastoma

Nature Communications 16, 3412 (2025).

Fernandes LF, Peeyatu C, Dickie BR, Ho YS, Thompson LA, Hernandez N, Lozano N, Kostarelos K*, Kisby T*.

Targeting therapeutic nanoparticles to the glioblastoma resection margin by harnessing post-operative spatiotemporal blood-brain barrier disruption.

bioRxiv 2025.03. 29.646102

Kisby T, Borst GR, Coope D, Kostarelos K

Targeting the glioblastoma resection margin with locoregional nanotechnologies.

Nature Reviews Clinical Oncology 22, pp. 517–537 (2025)

2024

Stylianou M, Kisby T*, Despotopoulou D, Parker H, Thawley A, Arashvand K, Lozano N, MacDonald AS, Kostarelos K*.

Engineering the glioblastoma microenvironment using TLR7/8 agonist-complexed graphene oxide nanosheets.

Cell Reports Physical Science Volume 6, Issue 1102342: 2025

2023

Sharp PS, Stylianou M, Arellano LM, Neves JC, Gravagnuolo AM, Dodd A, Barr K, Lozano N, Kisby T*, Kostarelos K*.

Graphene Oxide Nanoscale Platform Enhances the Anti‐Cancer Properties of Bortezomib in Glioblastoma Models.

Advanced Healthcare Materials. 2023 Jan;12(3):2201968.

Despotopoulou D, Stylianou M, Arellano LM, Kisby T, Lozano N, Kostarelos K*.

Engineering of a graphene oxide-based two-dimensional platform for immune activation and modulation.

bioRxiv. 2023 08.22.553542;

2021

Kisby T, Yilmazer A, Kostarelos K*.

Reasons for success and lessons learnt from nanoscale vaccines against COVID-19. Nature Nanotechnology. 2021 Aug;16(8):843-50.

Kisby T, de Lázaro I, Fisch S, Cartwright EJ, Cossu G, Kostarelos K*.

Adenoviral mediated delivery of OSKM factors induces partial reprogramming of mouse cardiac cells in vivo.

Advanced Therapeutics. 2021 Feb;4(2):2000141.

Kisby T, De Lázaro I, Stylianou M, Cossu G, Kostarelos K*.

Transient reprogramming of postnatal cardiomyocytes to a dedifferentiated state.

PloS one. 2021 May 5;16(5):e0251054.

2020

Shin Y, Vranic S, Just-Baringo X, Gali SM, Kisby T, Chen Y, Gkoutzidou A, Prestat E, Beljonne D, Larrosa I*, Kostarelos K*, Casiraghi C*.

Stable, concentrated, biocompatible, and defect-free graphene dispersions with positive charge.

Nanoscale. 2020 12(23):12383-94.

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